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1. THE NATURE OF SCIENCE 

A. The Scientific World View

By the end of the 8th grade, students should know that:

  • When similar investigations give different results, the scientific challenge is to judge whether the differences are trivial or significant, and it often takes further studies to decide. Even with similar results, scientists may wait until an investigation has been repeated many times before accepting the results as correct.
  • Scientific knowledge is subject to modification as new information challenges prevailing theories and as a new theory leads to looking at old observations in a new way.

By the end of the 12th grade, students should know that:

  • From time to time, major shifts occur in the scientific view of how the world works. More often, however, the changes that take place in the body of scientific knowledge are small modifications of prior knowledge. Change and continuity are persistent features of science.

B. Scientific Inquiry

By the end of the 8th grade, students should know that:

  • Scientists differ greatly in what phenomena they study and how they go about their work. Although there is no fixed set of steps that all scientists follow, scientific investigations usually involve the collection of relevant evidence, the use of logical reasoning, and the application of imagination in devising hypotheses and explanations to make sense of the collected evidence.
  • If more than one variable changes at the same time in an experiment, the outcome of the experiment may not be clearly attributable to any one of the variables. It may not always be possible to prevent outside variables from influencing the outcome of an investigation (or even to identify all of the variables), but collaboration among investigators can often lead to research designs that are able to deal with such situations.
  • What people expect to observe often affects what they actually do observe. Strong beliefs about what should happen in particular circumstances can prevent them from detecting other results. Scientists know about this danger to objectivity and take steps to try and avoid it when designing investigations and examining data. One safeguard is to have different investigators conduct independent studies of the same questions.
  • New ideas in science sometimes spring from unexpected findings, and they usually lead to new investigations.

By the end of the 12th grade, students should know that:

  • Investigations are conducted for different reasons, including to explore new phenomena, to check on previous results, to test how well a theory predicts, and to compare different theories.
  • Hypotheses are widely used in science for choosing what data to pay attention to and what additional data to seek, and for guiding the interpretation of the data (both new and previously available).
  • Sometimes, scientists can control conditions in order to obtain evidence. When that is not possible for practical or ethical reasons, they try to observe as wide a range of natural occurrences as possible to be able to discern patterns.

C. The Scientific Enterprise

By the end of the 8th grade, students should know that:

  • Computers have become invaluable in science because they speed up and extend people's ability to collect, store, compile, and analyze data, prepare research reports, and share data and ideas with investigators all over the world.
  • Accurate record-keeping, openness, and replication are essential for maintaining an investigator's credibility with other scientists and society.

By the end of the 12th grade, students should know that

  • Scientists can bring information, insights, and analytical skills to bear on matters of public concern. Acting in their areas of expertise, scientists can help people understand the likely causes of events and estimate their possible effects. Outside their areas of expertise, however, scientists should enjoy no special credibility. And where their own personal, institutional, or community interests are at stake, scientists as a group can be expected to be no less biased than other groups are about their perceived interests.

2.  THE LIVING ENVIRONMENT 

A. Diversity of Life

By the end of the 8th grade, students should know that

  • Similarities among organisms are found in internal anatomical features, which can be used to infer the degree of relatedness among organisms. In classifying organisms, biologists consider details of internal and external structures to be more important than behavior or general appearance.

By the end of the 12th grade, students should know that

  • The degree of kinship between organisms or species can be estimated from the similarity of their DNA sequences, which often closely matches their classification based on anatomical similarities.

B. Heredity

By the end of the 8th grade, students should know that

  • In some kinds of organisms, all the genes come from a single parent, whereas in organisms that have sexes, typically half of the genes come from each parent.

By the end of the 12th grade, students should know that

  • Genes are segments of DNA molecules. Inserting, deleting, or substituting DNA segments can alter genes. An altered gene may be passed on to every cell that develops from it. The resulting features may help, harm, or have little or no effect on the offspring's success in its environment.

C. Cells

By the end of the 8th grade, students should know that

  • Cells repeatedly divide to make more cells for growth and repair. Various organs and tissues function to serve the needs of cells for food, air, and waste removal.

By the end of the 12th grade, students should know that

  • The genetic information encoded in DNA molecules provides instructions for assembling protein molecules. The code used is virtually the same for all life forms.  Before a cell divides, the instructions are duplicated so that each of the two new cells gets all the necessary information for carrying on.

D. Evolution of Life

By the end of the 8th grade, students should know that

  • Small differences between parents and offspring can accumulate (through selective breeding) in successive generations so that descendants are very different from their ancestors.

By the end of the 12th grade, students should know that

  • The basic idea of biological evolution is that the earth's present-day species developed from earlier, distinctly different species.
  • Molecular evidence substantiates the anatomical evidence for evolution and provides additional detail about the sequence in which various lines of descent branched off from one another.
  • Natural selection leads to organisms that are well suited for survival in particular environments.  Chance alone can result in the persistence of some heritable characteristics having no survival or reproductive advantage or disadvantage for the organism.  When an environment changes, the survival value of some inherited characteristics may change.
  • The theory of natural selection provides a scientific explanation for the history of life on earth as depicted in the fossil record and in the similarities evident within the diversity of existing organisms.
  • Evolution builds on what already exists, so the more variety there is, the more there can be in the future.  But evolution does not necessitate long-term progress in some set direction.  Evolutionary changes appear to be like the growth of a bush:  Some branches survive from the beginning with little or no change, many die out altogether, and others branch repeatedly, sometimes giving rise to more complex organisms.
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