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A Plague of Frogs--Study Questions to accompany the book.
CHAPTER 12: We've Found Something in the Water"
1. What kinds of difficulties were appearing as the autumn of 1997 approached?
2. What ended the impasse?
3. What is FETAX?
4. What did the FETAX results show?
5. What does teratogenic mean?
6. Why did Judy Helgen decide to “tell everyone” about the results?
7. What is the Salk Institute in La Jolla?
8. What two essential considerations were the focus of the technical discussions?
9. What did this group believe was the only cause of leg malformations?
10. What did they think was the disruption?
11. What sensational claim did Dave Gardiner make?
12. What makes many steroid or vitamin-derived hormones so powerful?
13. What is a ligand?
14. What does the result of gene expression depend on?
15. What types of “housekeeping” functions do hormones perform?
16. What is an orphan receptor?
17. What might some potential practical benefits of this work be?
18. What were some of the unanswered questions that remained? Which deformities more common?
19. At this point in the investigation, what are the two main hypotheses about the cause of the outbreaks?
20. What did Sue Bryant think should be the main focus of the investigation?
21. Describe a limitation of the FETAX results.
22. What happened with the FETAX results after they were announced to the public?
23. How does the DNA of a frog compare to that of a human?
24. What did Stan Session use regeneration assays for?
25. What was the “diffusible morphogen” thought to do?
26. What did they speculate was the diffusible morphogen?
27. Why did Sue Bryant reject the diffusable morphogen theory?
28. What is Rana sylvatica and what did Stan Sessions useit to study?
29. How did Sessions know the parasites were trematodes?
30. Outline the basics of the parasite theory.
31. What is intercalation?
32. What was the estimated rate of traumatic amputation Ouellet saw in the field?
33. Why did Ouellet think the US investigation was “incompetent”?
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