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DOG, MANS BEST FRIEND
Introduction The canine genome project and the human genome project have been underway for the past few years. As scientists reach the end of these projects what information will be available for
research and further development. Will cloning be the only value? Or will this information be utilized by the medical and pharmaceutical industry in the detection of disease and the treatment of those
diseases. Do humans and dogs share some common genes? In fact 99% of human genes are also found in dogs.
Connecting Activity The following activity will send you to the reference area of your library or to a computer with Internet access. A search for some correlation between the two research projects
will be underway. There are numerous sites on the Internet that report information found on the various chromosomes and there is a direct link between humans and dogs. Can you find the genes or the loc
(location) for the following diseases?
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Gene
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Canine loc
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Human loc
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Breast Cancer early onset
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CFA9
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17q21
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Factor VIII (blood clotting)
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X
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Xq28
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Von Willebrand factor
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CFA16
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12p13.3
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Olfactory receptor
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CFA9
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17q21
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Pancreatic lipase
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Synt. 14
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10q26.1
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Summary: Dogs have been selectively bred for many generations where as the human has not. What are the positive and negative implications of random and selective breeding?
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