1997 WWLPT Biology Institute:  Life Cycles:  Reproduction & Embryological Development


Assisted Reproduction :  activities designed to introduced terminology and
                                                                some of  the ethical issues associated with the use
                                                                of  technology to help infertile couples
 

 
 Linda Hall
South Dearborn High School
Aurora, Indiana
 
 
Summary/Abstract
Instructor's Objectives
Target Age or Ability Group Audience
Teacher Instructions/Special Precautions
Materials & Equipment Needs
Background [Prior Knowledge or vocabulary necessary to complete activity]
The Student Lab
Method of Evaluation/Assessment
Extension/Reinforcement/Additional Ideas

 

 



Summary/Abstract  to top

The following activities are intended to follow a unit on human reproduction.  In light of  the increasing number of  infertile couples in the United States, these activities can be used to introduce several currently used methods of  assisted reproduction including in vitro fertilization and cryopreservation, and to generate discussion of  ethical issues related to these procedures.

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Instructor's Objectives to top to top


Target Audience or Age Group  to top  to top


 
  • Notes to the Teacher: to top

  • These activities are designed for students who have completed a unit on the  reproductive  tract and are familiar with normal functions.

    Preparation time needed: the only preparation required is for copying  student sheets.  For the     placemat activity, the questions may be cut and pasted so that both items are on the same 11" x 14" sheet prior to duplication or they may be printed on separate paper.  For use on the longer paper, the questions can be typed in an 8 point font in a single column.  The placemat shown was set-up using a word-perfect table in letter landscape.  It has been rotated and shrunk in the materials section for illustration purposes only.

    Class time needed:

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    Materials & Equipment Needs to top
    Hard copies of the placemat and accompanying questions
    One hard copy of  the role-playing sheet per class or one copy per individual participating
    Hard copies of  the case study for each student

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    Background to top
    [Prior Knowledge or Vocabulary Necessary to Complete Activity]
     Students need to have an understanding of the structure and function of  the human reproductive tracts.

    These activities help students answer:
    1.  what forms of assisted reproduction are currently available
    2.  under what circumstances assisted reproduction may be used
    3.  what viewpoints may be involved
    4.  how to make an informed decision concerning an ethical issue
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    The Student Lab to top

    Advertising Placemat

    Procedure:
    Read the information on the placemat and complete the questions provided.
    Questions:
        1.  Term for the situation in which one woman bears a child for another .
        2.  This method has been successful when male infertility is due to low sperm count.
        3.  Freezes and stores donar sperm for use in IUI or ICSI.
        4.  Which organ produces eggs and estrogen?
        5.  Which method combines  sperm and eggs in the lab and then places the embryo
                into the uterus?
        6.  Which method may be used to fertilize the egg of a surrogate?
        7.  Name the method used to transfer stored embryos.
        8.  Cryopreservation uses this substance  to freeze sperm and embryos without damage.
        9.  These structures use cilia to move eggs to the uterus.
       10.  ZIFT differs from IVF in that the developing embryo is placed into?
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    Role-playing Activity
     

    Introduction::  Several students will be assigned  roles designed to stimulate discussion concerning some of  the ethical issues involved in the implantation of  frozen embryos.
    Purpose:  The purpose of  this exercise is to provide a vehicle for  students to begin thinking about  various factors and viewpoints that may be involved in deciding whether the implantation of frozen embryos is a reasonable action.
    Materials:  hard copies of  scenario
                     resources for background information
    Procedure:  Students involved in the role-playing will read the description for their part and will enter the discussion assuming the role assigned as directed by the moderator (the instructor or a student).   If the roles are assigned  prior to the day of  the activity,  the students involved will do research that will help them play their role effectively.

    Meeting of the Committee to Oversee Ethical Treatment of Human Embryos

    Called to consider a request to implant stored embryos following the divorce of the parents.

    Background:  Human embryos retrieved during in vitro fertilization procedures may be frozen in liquid nitrogen (cryopreservation) and stored for decades.  Current technology results in 5-12 embryos per treatment cycle.  Legal principles concerning this relatively new procedure are not firmly established.  Currently, legal ownership of embryos belongs to the married couple from whom the gametes were obtained.  When there is no legal marriage, the woman signing the consent form is the owner.

    Ms. Ima D. Vorsay wants to have her 3  stored embryos implanted.  The embryos were obtained while she was married to Mr. A. Newman.

    The Committee

    The committee is composed of  four individuals who are knowledgeable about current reproductive technology and are concerned about the ethical treatment of stored embryos.

    Witnesses

    Ms. D. Vorsay - a  43 year old woman whose first attemps to achieve pregnancy through IVF failed.  She has since been divorced but still wants to try to have her own child.

    Mr. Newman - Ms. D. Vorsay is his ex-wife.  He has remarried and now has two children.  He has had a restraining order issued to block the use of  his frozen embryos and wants to have them destroyed.

    Mr. U. R. Okay - a mental health expert.  He conducted Ms. Vorsay's patient interview.  He is against allowing the procedure.  Ms. Vorsay is single, has a limited network of friends, and is currently taking care of her elderly mother who is near death.

    Ms. E. Array - a lawyer hired by Ms. Vorsay.  She specializes in reproductive technology cases and argues that since the divorce, the embryos are the property of  the mother, Ima Vorsay, and that any children that might develop have the right to be raised by their biological mother.

    Dr. I.M. Sure - the doctor runs the assisted reproduction technology (art) clinic storing the embryos in question.  He states that Ima meets the criteria for accepting patients.  She is capable of experiencing a healthy, successful pregnancy, does not have serious psychiatric disabilities, and is able to pay for the procedure.

    Following brief statements from each witness, the public will be invited to make short comments.  The committee members may question the witnesses and will then confer to make their recommendation.
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    Case Study Concerning In Vitro Fertilization
     

    Introduction:  There are a number of  new technologies that have been developed to assist infertile couples in their attempt to have children.  One such technique is called  In Vitro Fertilization (sometimes erroneously called test-tube babies).

    Purpose:  The purpose of  this case study is to encourage students to spend time generating multiple solutions when faced with any dilemma and to give them practice using one form of decision-making model for choosing a solution.
     

    Materials:  hard copies of  question/case study sheet

    Procedure:

    1.  Each group of students  will  use resource materials, including but not limited to the internet,  to accurately answer the questions at the top of  the hand-out.

    2.  Once the background information has been completed, each student is expected to read the case study at the bottom of the page and generate 5 separate solutions to the situation described.

    3.   When all members of the group have written individual solutions, they will share their ideas and make a list of  the five "best" solutions.  It is important to remember that the solution does not have to appeal to a student to be viable.

    4.   The  group now needs to choose 5 criteria by which to judge the solutions.  These criteria will vary from group to group.  The students in the group must reach a consensus as to what criteria fit the situation and reflect the attitudes and values of  the members of  the group.  Common criteria selected include but are not limited to such features as cost,  religious viewpoints,  health risks,  legal issues, etc.   Students should make a chart listing the criteria across the top and the solutions down the side.  Brainstorming may be used to generate a list of possible criteria.

    5.   Students next discuss the criteria one at a time assigning a rank to each solution with 1 being assigned to the best solution concerning that criteria and 5 assigned to the poorest.  Once the  chart is completed, the points  are totaled and the solution with the lowest total score should be the best solution for the situation.  If  the group is not happy with the solution, they  should rethink their criteria or try to generate more potential solutions.

    6.  The final step is to list 3 reasons other people might not agree with the solution chosen.

    7.   Each group will turn in one set of  question answers and will present their  solutions  and  explain their choice.    Students are encouraged to present this information in the form of a skit.  Other students are encourage to comment but not judge.

    In Vitro Fertilization Case Study

    Background Information  (use sources no more than 2 years old when possible)

    1.  What does the expression  "in vitro fertilization" mean?  What is the stated success rate for
               this procedure?
    2.  Who was the world's first test-tube baby ?  When and where was she born?
    3.  Explain the process involved.  You may make posters or transparencies to illustrate.
    4.  What are the costs for this procedure and what is included?
    5.  Under what circumstances might a couple choose to try IVF?
    6.  How might this process be used to choose the sex of a child?
    7.  Since more than one egg is fertilized at once, list 4 options for dealing with the embryos.
    8.  How many IVF clinics are operating in the United States?

    Situation

    The success of  this exercise depends upon your ability to picture yourself actually involved in the scenario described.

         You (the husband) are 36 and your wife is 35.  You have been trying to achieve a pregnancy for 5 years without success.  Following a battery of  tests, it was determined that your sperm count is high enough but that your wife's Fallopian tubes will not allow an ovum to reach the uterus.  You both have decided against several options already, including adoption and  use of a surrogate.  Your fertility expert explained IVF as another option.  You both decided to take this opportunity.  Several eggs were recovered and six are developing normally.   Studies have shown that implanting more than 3 embryos is too risky.  What ought you do with the six embryos?

    Methods of Evaluation/Assessment to top

    1.  Placemat:  Students will hand-in the question section that accompanies the placemat.  The questions could be used as a homework grade but may be collected for a drawing for some small reward.  One answer sheet is drawn from those turned in.  The answers are gone over in class and should the answers on the sheet drawn be incorrect, another is drawn in its place.
    2.  There is no formal assessment intended for the role-playing activity.
    3.  Case Study:  Evaluation methods may vary here.  Part of the grade for each group is for
         providing accurate information concerning the procedures involved in In Vitro Fertilization and
         cryopreservation.  The remainder of  the grade is for the group presentation concerning the
         decision-making process.  Role-playing to illustrate their decision-making is encouraged.
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    Extension/Reinforcement/Additional Ideas to top
    Placemat:  As an alternative, show students the sample placemat and have them generate their own, individually or in groups.   This same format can be used to generate placemats on other topics.
    Case study:  Each group of students can be given a different case study relative to the same topic or  to related topics such as the use of a surrogate.  In this format,  each group presents the information generated by the topic questions before presenting their solutions and decision.  This approach allows the class to learn about several related topics in the same time frame.
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    References Including Web Addresses to top
    Pictures of  Embryo Growth        http://www.ihr.com/igo/articles/embgrow.html
    "Human Embryo Cryopreservation ... "       http://www.givf.com/embryo_cryo1.html
    "Infertility Treatments and Procedures"http://www.ihr.com/ivfphoenix/fertbook/treatment.htm
    "Affording Infertility and Procedure Costs" http://www.ihr.com/ivfphoenix/fertbook/affording.htm
    "Reproductive Technologies".   The Science Teacher.  December 1988. p. 20
    "The Rights of Frozen Embryos".  Time. July 24, 1989.  p. 63
    "Test Screens Live 'Test Tube' Embryos".  Science News. Vol. 135
    "Gift of a new life".  The Cincinnati Enquirer. March 8, 1995
    "The Gods of  Fertility".  The New York Times.  July 8, 1997
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