Applications of Research in the Classroom

Lab Techniques in the Classroom

Collection of specimens – cataloging (using keys) and recording data (Microsoft Excel)
DNA extraction – micropipetting, examining extraction technique to reinforce cell biology
PCR – Low Tech/precision involved in temp control and data collection
PCR – High Tech requires access to thermal cycler
Sequences may be sent out for processing by a lab.

Lab Techniques vs. Manipulating, Analyzing, and Representing Data

Great format to focus on several points.

1. Integration of computer science and biology. (Web-based activites)

Students could pull a set of sequences and learn the processes necessary to align and subsequently develop a phylogenetic tree.

Use of NCBI data bases such as BLAST, Entrez, etc. for analysis of DNA sequences etc.

2. Examine what parts of genomes have been sequenced and why? Students must choose nuclear vs. mitochondrial DNA and why if they were to design a research project?

3. Accepted scientific format of research information.

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Internet Links

Genetics and Biotechnology

http://www.dnalc.org/Shockwave/pcranwhole.html
Cold springs harbor PCR reaction animation.

http://www.amnh.org/exhibitions/genomics/0_home/lab.html
Inside this classroom laboratory, visitors and classes of students isolate and sequence their own DNA. They learn the same techniques that researchers use in the molecular laboratory at the American Museum of Natural History: isolating, manipulating, analyzing and storing DNA data.

http://www.cshl.org/
Cold Springs Harbor Lab

http://vector.cshl.org/
DNA Learning Center

http://www.people.virginia.edu/~rjh9u/blkysc82.html
The Blue People of Kentucky

http://www.ncgr.org/
National Center for Genome Resources

http://www.tigr.org/
The Institute for Genome Research

http://dna2z.com/DNA-o-gram/encode.html
DNA-O-Gram: send a message in code

http://www.esp.org/foundations/genetics/classical/
Classic Papers in Genetics

http://www.hhmi.org/genetictrail/
Blazing a Genetic Trail-HHMI

http://stein.cshl.org/talks/BioWWW/chapter/
Introduction to Human Genome Computing via the World Wide Web

http://gslc.genetics.utah.edu/
The Natural History of Genes: Genetic Science Learning Center

http://www.ornl.gov/hgmis/
The Human Genome Project

http://www.biology.arizona.edu/
The Biology Project: Online karyotyping, human biology genetic problems and so much more!

http://www.kumc.edu/gec/
Genetics Education Center

http://www.ncbi.nlm.nih.gov/
National Center for Biotechnology Information BLAST, OMIM, ENTREZ, it's all here.

http://www.intouchlive.com/cancergenetics/
The Genetics of Cancer

http://www.dnafiles.org/about/index.html
NPR Public Radio DNA files

Evolution Web Sites

http://www.indiana.edu/~ensiweb/home.html
ENSI/SENSI Evolution and the Nature of Science Institutes-many hands-on activities.

www.pbs.org/wgbh/evolution/
PBS Evolution Series-much information and many activities.

http://www.woodrow.org/teachers/Teacher_Resources/CORE/WWNFF_Biology/wwnff_biology.html
Woodrow Wilson Teacher Institutes (Years 1991-2001) Some years specific to evolution-great activities

http://www.ncseweb.org/
National Center for Science Education Great support for the teaching of evolution.

http://tolweb.org/tree/phylogeny.html
The Tree of Life

http://www.ucmp.berkeley.edu/
The Museum of Paleontology

www.hoflink.com/~house/evolution.html
Ken's Web Site References: Evolution

General Websites

http://www.lakeshoreschools.k12.mi.us/mabt/
Lynda Smith's Class Links